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Invitrogen™ OAS3 Polyclonal Antibody
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Catalog No. PIPA597217
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100 μL
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PIPA597217 100 μL
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Catalog No. PIPA597217 Supplier Invitrogen™ Supplier No. PA597217
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: AASCYDHPCF LRGMGDPVQS WKGPGLPRAG CSGLGHPIQL DPNQKTPENS KSLNAVYPRA GSKPPSCPAP GPTGAASIVP SVPGMALDLS QIPTKELDRF IQDHLKPSPQ FQEQVKKAID IILRCLHENC VHKASRVSKG GSFGRGTDLR DGCDVELIIF LNCFTDYKDQ GPRRAEILDE MRAQLESWWQ DQVPSLSLQF PEQNVPEALQ FQLVSTALKS WTDVSLLPAF DAVGQLSSGT KPNPQVYSRL LTSGCQEGEH KACFAELRRN FMNIRPVKLK NLILLVKHWY RQVAAQNKGK G; Positive Samples: U-87MG, DU145, HeLa; Cellular Location: Cytoplasm, Nucleus.

OAS3 is an interferon inducible protein that belongs to the 2-5A synthetase family, may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. OAS3 synthesizes preferentially dimeric 2',5'-oligoadenylate molecules. GTP can be an alternative substrate. OAS3 binds double-stranded RNA and polymerizes ATP into PPP(A2'P5'A)N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. The protein is present at high level in placenta trophoblast.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OAS3
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.62 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene OAS3
Gene Accession No. Q5MYT7, Q8VI93, Q9Y6K5
Gene Alias (2-5')oligo(A) synthase 3; (2-5')oligo(A) synthetase 3; 2',5'-oligoadenylate synthetase-like 10; 2'-5' oligoadenylate synthetase 3; 2'-5' oligoadenylate synthetase-like 10; 2-5A synthase 3; 2-5A synthetase 3; 2'-5'-oligoadenylate synthase 3; 2'-5'-oligoadenylate synthetase 3; 2'-5'-oligoadenylate synthetase 3, 100kDa; 2'-5'oligoadenylate synthetase p100; Oas3; oasl10; P/OKcl.4; p100; p100 OAS; p100OAS
Gene Symbols OAS3
Host Species Rabbit
Immunogen Recombinant protein (or fragment)
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 246727, 4940, 494202
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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