Invitrogen™ OAS3 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5143138

Catalog No. PIPA5143138

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.

OAS3 is an interferon inducible protein that belongs to the 2-5A synthetase family, may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. OAS3 synthesizes preferentially dimeric 2',5'-oligoadenylate molecules. GTP can be an alternative substrate. OAS3 binds double-stranded RNA and polymerizes ATP into PPP(A2'P5'A)N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. The protein is present at high level in placenta trophoblast.

Specifications

• Antigen: OAS3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: OAS3
• Gene Alias: (2-5')oligo(A) synthase 3; (2-5')oligo(A) synthetase 3; 2',5'-oligoadenylate synthetase-like 10; 2'-5' oligoadenylate synthetase 3; 2'-5' oligoadenylate synthetase-like 10; 2-5A synthase 3; 2-5A synthetase 3; 2'-5'-oligoadenylate synthase 3; 2'-5'-oligoadenylate synthetase 3; 2'-5'-oligoadenylate synthetase 3, 100kDa; 2'-5'oligoadenylate synthetase p100; Oas3; oasl10; P/OKcl.4; p100; p100 OAS; p100OAS
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 4940
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9Y6K5
• Gene Symbols: OAS3
• Immunogen: Peptide with sequence C-HPIQLDPNQKTPENS.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG