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OAS3 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987773
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100 μL
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50-198-7773 100 μL
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Catalog No. 50-198-7773 Supplier Bioss Supplier No. BS7344R
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Rabbit Polyclonal Antibody

OAS3 is an interferon inducible protein that belongs to the 2-5A synthetase family, may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. OAS3 synthesizes preferentially dimeric 2′,5′-oligoadenylate molecules. GTP can be an alternative substrate. OAS3 binds double-stranded RNA and polymerizes ATP into PPP(A2′P5′A)N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. The protein is present at high level in placenta trophoblast.

Specifications

Antigen OAS3
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene OAS3
Gene Accession No. Q9Y6K5
Gene Alias (2-5′)oligo(A) synthase 3; (2-5′)oligo(A) synthetase 3; 2′,5′-oligoadenylate synthetase-like 10; 2′-5′ oligoadenylate synthetase 3; 2′-5′ oligoadenylate synthetase-like 10; 2-5A synthase 3; 2-5A synthetase 3; 2′-5′-oligoadenylate synthase 3; 2′-5′-oligoadenylate synthetase 3; 2′-5′-oligoadenylate synthetase 3, 100kDa; 2′-5′oligoadenylate synthetase p100; OAS3; oasl10; P/OKcl.4; p100; p100 OAS; p100OAS
Gene Symbols OAS3
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human OAS3.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4940
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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