OAS3 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 219151AP
DescriptionOAS3 is an interferon inducible protein that belongs to the 2-5A synthetase family, may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. OAS3 synthesizes preferentially dimeric 2 ft., 5 ft.-oligoadenylate molecules. GTP can be an alternative substrate. OAS3 binds double-stranded RNA and polymerizes ATP into PPP(A2 ft.P5 ft.A)N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. The protein is present at high level in placenta trophoblast.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|(2 5)oligo(A) synthase 3, 2 5 oligoadenylate synthase 3, 2 5A synthase 3, OAS3, p100, p100 OAS, p100OAS|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|OAS3 Fusion Protein Ag16150|
|Antigen Affinity Chromatography|
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