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Invitrogen™ OASL Polyclonal Antibody
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Catalog No. PIPA581946
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PIPA581946 100 μL
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Catalog No. PIPA581946 Supplier Invitrogen™ Supplier No. PA581946
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EVLDAVRTVE EFLRQEHFQG KRGLDQDVRV LKVVKVGSFG NGTVLRSTRE VELVAFLSCF HSFQEAAKHH KDVLRLIWKT MWQSQDLLDL GLEDLRMEQR VPDALVFTIQ TRGTAEPITV TIVPAYRAL Highest antigen sequence indentity to the following orthologs: Mouse - 70%, Rat - 72%.

2-prime,5-prime oligoadenylates (2-5As) bind to and activate RNase L, leading to degradation of RNA and inhibition of protein synthesis. 2-5As are produced by 2-5A synthetases (OASs), a highly-conserved family of interferon-induced enzymes. The predicted 514-amino acid human p59OASL (2-5A synthetases-like) protein shares a highly conserved N-terminal domain with other OASs. The C-terminal portion of p59OASL contains 2 ubiquitin-like domains. p59OASL is expressed in most tissues, with the highest levels in hematopoietic tissues, colon, and stomach.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OASL
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene OASL
Gene Accession No. Q15646
Gene Alias 2',5'-oligoadenylate synthetase-like 9; 2,5-oligoadenylate synthetase-like 9; 2'-5' oligoadenylate synthetase-like 1; 2'-5'-OAS-related protein; 2'-5'-OAS-RP; 2'-5'-oligoadenylate synthase-like protein; 2'-5'-oligoadenylate synthase-like protein 1; 2'-5'-oligoadenylate synthetase like; 2'-5'-oligoadenylate synthetase-like; 59 kDa 2'-5'-oligoadenylate synthase-like protein; 59 kDa 2'-5'-oligoadenylate synthetase-like protein; 7530414C13Rik; OASL; Oasl1; oasl9; OASLd; p59 OASL; p59OASL; p59-OASL; Thyroid receptor-interacting protein 14; TR-interacting protein 14; TRIP14; TRIP-14
Gene Symbols OASL
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human OASL. Recombinant protein control fragment (Product #RP-99399).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8638
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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