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Invitrogen™ OASL Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA581946

Catalog No. PIPA581946


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Description

Description

Immunogen sequence: EVLDAVRTVE EFLRQEHFQG KRGLDQDVRV LKVVKVGSFG NGTVLRSTRE VELVAFLSCF HSFQEAAKHH KDVLRLIWKT MWQSQDLLDL GLEDLRMEQR VPDALVFTIQ TRGTAEPITV TIVPAYRAL.

2-prime,5-prime oligoadenylates (2-5As) bind to and activate RNase L, leading to degradation of RNA and inhibition of protein synthesis. 2-5As are produced by 2-5A synthetases (OASs), a highly-conserved family of interferon-induced enzymes. The predicted 514-amino acid human p59OASL (2-5A synthetases-like) protein shares a highly conserved N-terminal domain with other OASs. The C-terminal portion of p59OASL contains 2 ubiquitin-like domains. p59OASL is expressed in most tissues, with the highest levels in hematopoietic tissues, colon, and stomach.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

OASL
Polyclonal
Unconjugated
OASL
2',5'-oligoadenylate synthetase-like 9; 2,5-oligoadenylate synthetase-like 9; 2'-5' oligoadenylate synthetase-like 1; 2'-5'-OAS-related protein; 2'-5'-OAS-RP; 2'-5'-oligoadenylate synthase-like protein; 2'-5'-oligoadenylate synthase-like protein 1; 2'-5'-oligoadenylate synthetase like; 2'-5'-oligoadenylate synthetase-like; 59 kDa 2'-5'-oligoadenylate synthase-like protein; 59 kDa 2'-5'-oligoadenylate synthetase-like protein; 7530414C13Rik; OASL; Oasl1; oasl9; OASLd; p59 OASL; p59OASL; p59-OASL; Thyroid receptor-interacting protein 14; TR-interacting protein 14; TRIP14; TRIP-14
Rabbit
Antigen affinity chromatography
RUO
8638
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot, Immunocytochemistry
0.1 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q15646
OASL
Recombinant protein corresponding to Human OASL. Recombinant protein control fragment (Product #RP-99399).
100 μL
Primary
Human
Antibody
IgG
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