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Invitrogen™ OATP2 Monoclonal Antibody (ESL)
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Catalog No. MA3934
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100 μL
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Catalog No. Quantity
MA3934 100 μL
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Catalog No. MA3934 Supplier Invitrogen™ Supplier No. MA3934
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Description

Mouse Monoclonal Antibody

MA3-934 detects OATP from human tissue and cells. This antibody does not detect dog, mouse or rat protein. MA3-934 shows no cross-reactivity to other OATP isoforms. MA3-934 has been successfully used in immunofluorescence, western blotting, and immunoprecipitation procedures. Immunofluorescence staining of OATP2 in human liver samples results in a pattern consistent with plasma membrane staining. The MA3-934 immunogen is a synthetic peptide corresponding to residues E(671) S L N K N K H F V P S A G A D S E T H C(691) of human OATP2.

A liver-specific member of the organic anion transporter family. This protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OATP2
Applications Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone ESL
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation tissue culture supernatant with 0.09% sodium azide
Gene SLCO1B1
Gene Accession No. Q9Y6L6
Gene Alias HBLRR; liver-specific organic anion transporter 1; LST1; LST-1; OATP1B1; OATP2; OATP-2; OATPC; OATP-C; SLC01B1; SLC21A6; SLCO1B1; Sodium-independent organic anion-transporting polypeptide 2; solute carrier family 21 (organic anion transporter), member 6; Solute carrier family 21 member 6; Solute carrier organic anion transporter family member 1B1; solute carrier organic anion transporter family, member 1B1
Gene Symbols SLCO1B1
Host Species Mouse
Immunogen Synthetic peptide corresponding to residues E(671) S L N K N K H F V P S A G A D S E T H C(691) of human OATP2.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10599
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgM
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