OATP2 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA5106753

Catalog No. PIPA5106753

Description

Antibody detects endogenous levels of total SLCO1B1.

AP9609c is a liver-specific member of the organic anion transporter family. This protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function.

Specifications

• Antigen: OATP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLCO1B1
• Gene Alias: HBLRR; liver-specific organic anion transporter 1; LST1; LST-1; OATP1B1; OATP2; OATP-2; OATPC; OATP-C; SLC01B1; SLC21A6; SLCO1B1; Sodium-independent organic anion-transporting polypeptide 2; solute carrier family 21 (organic anion transporter), member 6; Solute carrier family 21 member 6; Solute carrier organic anion transporter family member 1B1; solute carrier organic anion transporter family, member 1B1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10599
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9Y6L6
• Gene Symbols: SLCO1B1
• Immunogen: A synthesized peptide derived from human SLCO1B1(Accession Q9Y6L6), corresponding to amino acid residues A257-Q307.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov