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Invitrogen™ OATP8 Polyclonal Antibody
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Catalog No. PIPA582186
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100 μL
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PIPA582186 100 μL
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Catalog No. PIPA582186 Supplier Invitrogen™ Supplier No. PA582186
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: QGKDTKASDN ERKVMDEANL EFLNNGEHFV PSAGTDSKTC NLDMQDNAAA Highest antigen sequence indentity to the following orthologs: Mouse - 33%, Rat - 32%.

SLCO1B3, also known as OATP8 or OATP1B3, is a member of Organic Anion Transporting Polypeptides (OATPs) which are sodium-independent organic anion transporters mediating the uptake of a wide range of structurally diverse endogenous and exogenous compounds including bile acids, hormone conjugates, peptides, toxins, as well as a multitude of therapeutic drugs. SLCO1B3 is specifically expressed in liver under normal condition, while its expression has also been observed in cancer tissues like colon, prostate and pancreas. The molecular mass of SLCO1B3 is highly dependent on the glycosylation modification (deglycosylated form of 65 kDa, fully-glycosylated form of 120 kDa).
TRUSTED_SUSTAINABILITY

Specifications

Antigen OATP8
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SLCO1B3
Gene Accession No. Q9NPD5
Gene Alias HBLRR; liver-specific organic anion transporter 2; liver-specific organic anion transporter 3TM13; LST2; LST-2; LST3; LST-3TM13; OATP1B3; OATP8; OATP-8; Organic anion transporter 8; organic anion transporter LST-3c; organic anion-transporting polypeptide 8; SLC21A8; SLCO1B3; solute carrier family 21 (organic anion transporter), member 8; Solute carrier family 21 member 8; Solute carrier organic anion transporter family member 1B3; solute carrier organic anion transporter family, member 1B3
Gene Symbols SLCO1B3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SLCO1B3. Recombinant protein control fragment (Product #RP-101761).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 28234
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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