Invitrogen™ OAZ3 Polyclonal Antibody

Catalog No.	Quantity
PIPA5103992	100 μL

Catalog No. PIPA5103992

Supplier: Invitrogen™ PA5103992

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total OAZ3.

The antizyme family is a group of small proteins that play a role in cell growth and division by regulating the biosynthesis of polyamines such as putrescine, spermidine and spermine. AZ3, also known as OAZ3 (Ornithine decarboxylase antizyme 3), is a 187 amino acid protein that belongs to the ODC antizyme family. AZ3 probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells because it binds to, and destabilizes, ornithine decarboxylase. However, mutations in the AZ3 gene are not a common cause of male infertility and the normal AZ3 protein does not accelerate ornithine decarboxylase degeneration. AZ3 expression has a sharp onset in early spermatids, peaks in later stages and is gone in spermatozoa.

Specifications

• Antigen: OAZ3
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: OAZ3
• Gene Accession No.: A1BPI0, Q9R109, Q9UMX2
• Gene Alias: antizyme 3; AZ3; Az-3; OAZ3; OAZ-t; ODC-Az 3; ornithine decarboxylase antizyme 3; testicular secretory protein Li 31; testis specific ornithine decarboxylase antizyme; TISP15
• Gene Symbols: OAZ3
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human OAZ3(Accession Q9UMX2), corresponding to amino acid residues E159-A209.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 51686, 53814, 689588
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

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