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Invitrogen™ OAZ3 Polyclonal Antibody
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Catalog No. PIPA565056
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100 μL
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PIPA565056 100 μL
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Catalog No. PIPA565056 Supplier Invitrogen™ Supplier No. PA565056
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VNFQNDRNDRG ALLRAFSYMG FEVVRPDHPA LPPLDNVIFM VYPLERDVGH LPSEPP Highest antigen sequence identity to the following orthologs - mouse 82%, rat 77%.

The antizyme family is a group of small proteins that play a role in cell growth and division by regulating the biosynthesis of polyamines such as putrescine, spermidine and spermine. AZ3, also known as OAZ3 (Ornithine decarboxylase antizyme 3), is a 187 amino acid protein that belongs to the ODC antizyme family. AZ3 probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells because it binds to, and destabilizes, ornithine decarboxylase. However, mutations in the AZ3 gene are not a common cause of male infertility and the normal AZ3 protein does not accelerate ornithine decarboxylase degeneration. AZ3 expression has a sharp onset in early spermatids, peaks in later stages and is gone in spermatozoa.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OAZ3
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene OAZ3
Gene Accession No. Q9UMX2
Gene Alias antizyme 3; AZ3; Az-3; OAZ3; OAZ-t; ODC-Az 3; ornithine decarboxylase antizyme 3; testicular secretory protein Li 31; testis specific ornithine decarboxylase antizyme; TISP15
Gene Symbols OAZ3
Host Species Rabbit
Immunogen Recombinant Human OAZ3. Recombinant protein control fragment (Product #RP-105822).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51686
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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