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Invitrogen™ OBFC2A Polyclonal Antibody
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Catalog No. PIPA5100163
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100 μL
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PIPA5100163 100 μL
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Catalog No. PIPA5100163 Supplier Invitrogen™ Supplier No. PA5100163
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total OBFC2A.

NABP1, also known as NABP1/Ssb2, is a single-stranded DNA-binding protein involved in genome maintenance and stability. The gene encoding NABP1 is regulated by RORgamma2, a retinoid-related orphan receptor critical for thymopoiesis. Research has demonstrated that NABP1 plays a compensatory role in thymic maturation, particularly in conditions where its homolog, SSB1, is knocked out. Despite SSB1's vital role in neonatal survival, NABP1 remains non-essential for thymic maturation and male fertility, indicating partial functional redundancy between these proteins. Furthermore, studies on the C-terminal regions of NABP1 have shown distinct roles in nucleic acid binding, contributing to DNA and RNA metabolism. These findings highlight NABP1's importance in genomic integrity and its complex interplay within cellular processes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OBFC2A
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene NABP1
Gene Accession No. Q96AH0
Gene Alias 4930434H03Rik; 4930442A21Rik; 4930488J04Rik; 4933440J18Rik; 5830411E10Rik; AI852561; hSSB2; Nabp1; Nbp1; nucleic acid binding protein 1; nucleic acid-binding protein 1; Obfc2a; oligonucleotide/oligosaccharide-binding fold containing 2A; oligonucleotide/oligosaccharide-binding fold-containing protein 2A; RGD1306658; Sensor of single-strand DNA complex subunit B2; sensor of ssDNA subunit B2; Single-stranded DNA-binding protein 2; SOSS complex subunit B2; SOSS-B2; Ssb2
Gene Symbols NABP1
Host Species Rabbit
Immunogen A synthesized peptide derived from human NABP1(Accession Q96AH0), corresponding to amino acid residues E114-S164.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64859
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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