Invitrogen™ OBFC2B Monoclonal Antibody (OTI1E11)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA525801

Catalog No. PIMA525801

Description

OBFC2B Monoclonal Antibody for Western Blot, IHC (P), Flow

Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.

Specifications

• Antigen: OBFC2B
• Classification: Monoclonal
• Concentration: 0.45 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9BQ15
• Gene Symbols: NABP2
• Immunogen: Full length human recombinant protein of OBFC2B produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1E11
• Conjugate: Unconjugated
• Gene: NABP2
• Gene Alias: 2610036N15Rik; hSSB1; LP3587; Nabp2; nucleic acid binding protein 2; nucleic acid-binding protein 2; Obfc2b; oligonucleotide/oligosaccharide-binding fold containing 2B; oligonucleotide/oligosaccharide-binding fold-containing protein 2B; RGD1308158; Sensor of single-strand DNA complex subunit B1; sensor of ssDNA subunit B1; single strand DNA-binding protein 1; single-stranded DNA-binding protein 1; SOSS complex subunit B1; SOSS-B1; SSB1
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 79035
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid