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Invitrogen™ OBFC2B Polyclonal Antibody
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Catalog No. PA548241
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400 μL
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PA548241 400 μL
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Catalog No. PA548241 Supplier Invitrogen™ Supplier No. PA548241
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Rabbit Polyclonal Antibody

Predicted to react with bovine and rat based on sequence homology.

Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OBFC2B
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene NABP2
Gene Accession No. Q8R2Y9, Q9BQ15
Gene Alias 2610036N15Rik; hSSB1; LP3587; Nabp2; nucleic acid binding protein 2; nucleic acid-binding protein 2; Obfc2b; oligonucleotide/oligosaccharide-binding fold containing 2B; oligonucleotide/oligosaccharide-binding fold-containing protein 2B; RGD1308158; Sensor of single-strand DNA complex subunit B1; sensor of ssDNA subunit B1; single strand DNA-binding protein 1; single-stranded DNA-binding protein 1; SOSS complex subunit B1; SOSS-B1; SSB1
Gene Symbols NABP2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 183-211 amino acids from the C-terminal region of human OBFC2B.
Purification Method Antigen affinity chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 69917, 79035
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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