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Invitrogen™ OBFC2B Polyclonal Antibody
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Catalog No. PIPA560779
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100 μL
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PIPA560779 100 μL
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Catalog No. PIPA560779 Supplier Invitrogen™ Supplier No. PA560779
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GGGPHPPHTP SHPPSTRITR SQPNHTPAGP Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 87%.

Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OBFC2B
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NABP2
Gene Accession No. Q9BQ15
Gene Alias 2610036N15Rik; hSSB1; LP3587; Nabp2; nucleic acid binding protein 2; nucleic acid-binding protein 2; Obfc2b; oligonucleotide/oligosaccharide-binding fold containing 2B; oligonucleotide/oligosaccharide-binding fold-containing protein 2B; RGD1308158; Sensor of single-strand DNA complex subunit B1; sensor of ssDNA subunit B1; single strand DNA-binding protein 1; single-stranded DNA-binding protein 1; SOSS complex subunit B1; SOSS-B1; SSB1
Gene Symbols NABP2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human OBFC2B. Recombinant protein control fragment (Product #RP-97772).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79035
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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