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  6. Invitrogen™ Occludin Recombinant Rabbit Monoclonal Antibody (BLR126H)

Invitrogen™ Occludin Recombinant Rabbit Monoclonal Antibody (BLR126H)
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Catalog No. PIMA544441
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100 μL
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PIMA544441 100 μL
PIMA544442 20 μL
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Catalog No. PIMA544441 Supplier Invitrogen™ Supplier No. MA544441
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Description

Rabbit Recombinant Monoclonal Antibody

Occludin Recombinant Monoclonal Antibody for Western Blot, IP

Occludin is a 65 kDa protein that can exist in a variety of phosphorylated forms, ranging up to approximately 82 kDa. Occludin is thought to be involved in regulating both the localization and the function of occludin. Polyunsaturated fatty acids are known to up-regulate occludin expression, increasing the transendothelial cell resistance and reducing the cellular permeability to large molecules. The level of occludin varies greatly depending on tissue; in brain tissue, occludin is highly and continuously expressed at cell-cell contact sites, whereas non-neural tissues show lower expression and discontinuous distribution. Overall structural features of the occludin protein are highly conserved in all the species examined. Under-expression of tight junction proteins, including occludin, is a key molecular abnormality responsible for the increased permeability of tumor endothelial tight junctions, which contributes to brain tumor edemas.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Occludin
Applications Immunoprecipitation, Western Blot
Classification Recombinant Monoclonal
Clone BLR126H
Concentration 100 μg/mL
Conjugate Unconjugated
Formulation BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene OCLN
Gene Accession No. Q16625
Gene Alias AI503564; BLCPMG; Occludin; occludin 1B; Ocl; Ocln; phosphatase 1, regulatory subunit 115; PPP1R115; tight junction protein occludin; tight junction structural protein
Gene Symbols OCLN
Host Species Rabbit
Immunogen Peptide representing a region between residue 472 and the C-terminus (residue 522) of Human occludin.
Purification Method Purified
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100506658
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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