Invitrogen™ OCT1 (POU2F1) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120490

Catalog No. PIPA5120490

Description

Positive test controls include: Rat kidney. The target is usually found in the following locations: Nucleus. Immunogen sequence: NPSETSKPSM ESGDGNTGTQ TNGLDFQKQP VPVGGAISTA QAQAFLGHLH QVQLAGTSLQ AAAQSLNVQS KSNEESGDSQ QPSQPSQQPS VQAAIPQTQL MLAGGQITGL TLTPAQQQLL LQQAQAQAQL LAAAVQQHSA SQQHSAAGAT ISASAATPMT QIPLSQPIQI AQDLQQLQQL QQQNLNLQQF VLVHPTTNLQ PAQFIISQTP QGQQGLLQAQ NLLTQLPQQS QANLLQSQPS ITLTSQPATP TRTIAATPIQ TLPQSQSTPK RIDTPS.

OCT1 (POU2F1) is a ubiquitously expressed transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. It modulates transcription transactivation by NR3C1, AR and PGR. In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.

Specifications

• Antigen: OCT1 (POU2F1)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: POU2F1
• Gene Alias: 2810482H01Rik; NF-A1; OCT1; oct-1; oct-1B; octamer binding protein 1; octamer-binding protein 1; Octamer-binding transcription factor 1; Octamer-binding transcription factor-1; Otf1; OTF-1; POU class 2 homeobox 1; POU domain, class 2, transcription factor 1; Pou2f1; ubiquitous transcription factor
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 171068, 18986
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.68 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P25425, P31503
• Gene Symbols: POU2F1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 15-290 of human POU2F1/OCT1 (NP_001185712.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG