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Tocris Bioscience™ OD1
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Catalog No. 594110U
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Quantity:
10 μg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent hNav1.4, rNav1.6 and rNav1.7 channel activator

OD1 is a potent rat Nav1.7, human Nav1.4 and rat Nav1.6 channel activator (EC50 values are 7, 10 and 47 nM, respectively). Exhibits minimal activation at mammalian Nav1.2, Nav1.3 and Nav1.5 (EC50 values >3 μM). Inhibits fast inactivation on all channels. Increases peak currents at all voltages and stimulates a persistent Na+ current at hNav1.7 channel. Increases hyperpolarization at Nav1.4 and Nav1.6 channels. Induces spontaneous pain in vivo.

Specifications

Purity 95%
Content And Storage Store at -20°C
Description Voltage-gated Sodium Channel Blockers
Molecular Weight (g/mol) Observed M.W.: 7206.1
Quantity 10 μg
Structural Form C308H466N90O95S8
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