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Thermo Scientific Chemicals Ofloxacin, 98%, Thermo Scientific Chemicals

Catalog No. AC455670050
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AC455670250 25 g
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Ofloxacin, CAS # 82419-36-1, is a fluoroquinolone antibiotic with broad antibacterial activity against gram-positive and -negative bacteria, as well as against mycobacteria.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Ofloxacin is a synthetic fluoroquinolone antibiotic that is an analog of nalidixic acid
  • Ofloxacin can directly interact with pneumococcal autolysin (LytA) at its choline binding domain, thus inhibiting the ability of LytA to degrade the pneumococcal cell wall
  • Ofloxacin is racemic and its (S)-enantiomer is levofloxacin

Applications

  • Ofloxacin may be used in pharmacokinetic laboratory studies and high-throughput drug screens
  • The DNA and protein-binding capabilities of ofloxacin have been studied in the laboratory
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 82419-36-1
Molecular Formula C18H20FN3O4
Molecular Weight (g/mol) 361.373
InChI Key GSDSWSVVBLHKDQ-UHFFFAOYSA-N
PubChem CID 4583
ChEBI CHEBI:7731
SMILES CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O

Specifications

Type Ofloxacin
Melting Point 280.0°C to 275.0°C
Infrared Spectrum Authentic
Loss on Drying 0.2% max.
Quantity 5 g
Solubility Information Solubility in water: slightly soluble.
Formula Weight 361.37
Percent Purity 98%
Chemical Name or Material Ofloxacin

RUO – Research Use Only

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