Invitrogen™ OGT Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA522092

Catalog No. PIPA522092

Description

Recommended positive controls: HeLa, mouse brain, PC-12, Rat2. Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (100%), Pig (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Specifications

• Antigen: OGT
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: OGT
• Gene Alias: 1110038P24Rik; 4831420N21Rik; AI115525; FLJ23071; HINCUT-1; HRNT1; MGC22921; O linked N-acetylglucosamine transferase; O-GLCNAC; o-glcnac transferase; O-GlcNAc transferase p110 subunit; O-GlcNAc transferase subunit p110; OGT; Ogtl; O-linked N-acetylglucosamine (GlcNAc) transferase; O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase); O-linked N-acetylglucosamine transferase; O-linked N-acetylglucosamine transferase 110 kDa subunit; UDP-N-acetylglucosamine:polypeptide-N- acetylglucosaminyl transferase; UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase; UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit; uridinediphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyl transferase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 108155, 26295, 8473
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O15294, P56558, Q8CGY8
• Gene Symbols: OGT
• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human O-GlcNAc transferase. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG