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Invitrogen™ OLFM1 Polyclonal Antibody
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Catalog No. PIPA587397
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100 μL
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PIPA587397 100 μL
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Catalog No. PIPA587397 Supplier Invitrogen™ Supplier No. PA587397
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: IEVLDRRTQR DLQYVEKMEN QMKGLESKFK QVEESHKQHL ARQFKAIKAK MDELRPLIPV LEEYKADAKL VLQFKEEVQN LTSVLNELQE EIGAYDYDEL QSRVSNLEER LRACMQKLAC GKLTGISDPV T; Positive Samples: Mouse brain, MCF7, A-549, SW480; Cellular Location: Cell junction, Cell projection, Endoplasmic reticulum, Perikaryon, axon, synapse.

The Olfactomedin family comprises a diverse group of secreted glycoproteins, which includes OLFM1 (Noelin-1), OLFM2 (Noelin-2), OLFM3 (Noelin-3), OLFM4 (Noelin-4), tiarin, pancortin, gliomedin and mycocilin. These proteins are implicated in the development of the nervous system. Specifically, OLFM1 and OLFM2 expression is observed in the neural plate and neural crest, as well as in the cranial ganglia in mouse at E8-10, and later in brain tissue and in the zone of polarizing activity in the limb. Overexpression of OLFM1 causes an excess of neural crest emigrations and prolonged neural crest production. OLFM2 participates in the regulation of the development of the anterior nervous system. An Arg144Gln mutation in OLFM2 has been implicated as a possible cause for open-angle glaucoma (OAG).
TRUSTED_SUSTAINABILITY

Specifications

Antigen OLFM1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.35 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene OLFM1
Gene Accession No. O88998, Q99784
Gene Alias 1B426B; AMY; AW742568; D2Sut1e; neuroblastoma protein; neuronal olfactomedin-related ER localized protein; Noe1; Noel; Noel1; Noelin; Noelin 1; Noelin 2; NOELIN1; OlfA; olfactomedin 1; olfactomedin related ER localized protein; olfactomedin-1; OLFM1; Pancortin; pancortin 1; Pancortin 1-4; Pancortin3
Gene Symbols OLFM1
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10439, 56177
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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