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Invitrogen™ OLFM3 Polyclonal Antibody
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Catalog No. PIPA5110059
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100 μL
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PIPA5110059 100 μL
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Catalog No. PIPA5110059 Supplier Invitrogen™ Supplier No. PA5110059
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: HQRVLSLETR LRDCMKKLTC GKLMKITGPI TVKTSGTRFG AWMTDPLASE KNNRVWYMDS YTNNKIVREY KSIADFVSGA ESRTYNLPFK WAGTNHVVYN G.

OLFM3 (olfactomedin 3), also known as NOE3, is a 478 amino acid protein that interacts with myocilin. Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure. OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins. OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue. Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OLFM3
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 2.87 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Olfm3
Gene Accession No. P63056, P63057, Q96PB7
Gene Alias B230206G02Rik; NOE3; NOELIN3; Noelin-3; olfactomedin 3; olfactomedin related ER localized protein 3; olfactomedin-3; OLFM3; OPTIMEDIN; UNQ1924/PRO4399
Gene Symbols Olfm3
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 118427, 229759, 252920
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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