Invitrogen™ OLFM3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110059

Catalog No. PIPA5110059

Description

Immunogen sequence: HQRVLSLETR LRDCMKKLTC GKLMKITGPI TVKTSGTRFG AWMTDPLASE KNNRVWYMDS YTNNKIVREY KSIADFVSGA ESRTYNLPFK WAGTNHVVYN G.

OLFM3 (olfactomedin 3), also known as NOE3, is a 478 amino acid protein that interacts with myocilin. Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure. OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins. OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue. Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.

Specifications

• Antigen: OLFM3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Olfm3
• Gene Alias: B230206G02Rik; NOE3; NOELIN3; Noelin-3; olfactomedin 3; olfactomedin related ER localized protein 3; olfactomedin-3; OLFM3; OPTIMEDIN; UNQ1924/PRO4399
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 118427, 229759, 252920
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.87 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P63056, P63057, Q96PB7
• Gene Symbols: Olfm3
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of mouse OLFM3 (NP_6947971).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG