Invitrogen™ OLFM3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550866

Catalog No. PA550866

Description

The antibody detects endogenous levels of total OLFM3 protein.

OLFM3 (olfactomedin 3), also known as NOE3, is a 478 amino acid protein that interacts with myocilin. Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure. OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins. OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue. Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.

Specifications

• Antigen: OLFM3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Olfm3
• Gene Alias: B230206G02Rik; NOE3; NOELIN3; Noelin-3; olfactomedin 3; olfactomedin related ER localized protein 3; olfactomedin-3; OLFM3; OPTIMEDIN; UNQ1924/PRO4399
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 118427, 229759
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P63056, Q96PB7
• Gene Symbols: Olfm3
• Immunogen: Fusion protein corresponding to residues near the C terminal of human olfactomedin 3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG