OLFM3 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIPA5121727	Invitrogen™ PA5121727	20 μL
PIPA5121726	Invitrogen™ PA5121726	100 μL

Description

OLFM3 (olfactomedin 3), also known as NOE3, is a 478 amino acid protein that interacts with myocilin. Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure. OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins. OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue. Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.

Specifications

• Antigen: OLFM3
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: Q96PB7
• Gene ID (Entrez): 118427
• Immunogen: Gln24-Glu198 (Accession Q96PB7), with N-terminal His Tag.
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: Olfm3

• Concentration: 0.5 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Alias: B230206G02Rik; NOE3; NOELIN3; Noelin-3; olfactomedin 3; olfactomedin related ER localized protein 3; olfactomedin-3; OLFM3; OPTIMEDIN; UNQ1924/PRO4399
• Gene Symbols: Olfm3
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody