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Invitrogen™ OLFM4 Polyclonal Antibody
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Catalog No. PIPA5116619
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100 μL
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PIPA5116619 100 μL
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Catalog No. PIPA5116619 Supplier Invitrogen™ Supplier No. PA5116619
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Description

Rabbit Polyclonal Antibody

Positive Samples: PC-3, Mouse spleen, Mouse stomach, Rat stomach Immunogen sequence: AIRREIVALK TKLKECEASK DQNTPVVHPP PTPGSCGHGG VVNISKPSVV QLNWRGFSYL YGAWGRDYSP QHPNKGLYWV APLNTDGRLL EYYRLYNTLD DLLLYINARE LRITYGQGSG TAVYNNNMYV NMYNTGNIAR VNLTTNTIAV TQTLPNAAYN NRFSYANVAW QDIDFAVDEN GLWVIYSTEA STGNMVISKL NDTTLQVLNT WYTKQYKPSA SNAFMVCGVL YATRTMNTRT EEIFYYYDTN TGKEGKLDIV MHKMQEKVQS INYNPFDQKL YVYNDGYLLN YDLSVLQKPQ.

OLFM4 is a 510 amino acid extracellular matrix glycoprotein belonging to the olfactomedin-related protein family and found to be selectively expressed in inflammed colonic epithelium. It has one signal peptide, six N-linked glycosylation motif and forms disulfide-bonded multimers. OLFM4 a transcription factor may have a matrix-related function in differentiation. Constitutively expressed OLFM4 in cancer cells binds to the potent apoptosis inducer GRIM-19 and has a novel antiapoptotic action and hence might serve as a diagnostic marker for human cancers. Reports suggest that OLFM4 promotes proliferation of PANC-1 cells by favoring transition from the S to G2/M phase. Potential interaction of OLFM4 with endogenous cell surface lectins and cadherins may mediate cell adhesion.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OLFM4
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 6.18 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene OLFM4
Gene Accession No. Q3UZZ4, Q6UX06
Gene Alias Antiapoptotic protein GW112; bA209J19.1; GC1; G-CSF-stimulated clone 1 protein; Gm296; Gm913; GW112; hGC-1; hOLfD; olfactomedin 4; olfactomedin-4; OlfD; OLFM4; OLM4; pPD4; PU.1 difference product 4; UNQ362; UNQ362/PRO698
Gene Symbols OLFM4
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 211-510 of human OLFM4 (NP_0064093).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10562, 290409, 380924
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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