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OLFM4 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA532954
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50 μg
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PIPA532954 50 μg
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Catalog No. PIPA532954 Supplier Thermo Scientific Supplier No. PA532954

Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset (100%) Guinea pig (94%) Orangutan, Rat, Hamster, Dog, Rabbit (88%).

OLFM4 is a 510 amino acid extracellular matrix glycoprotein belonging to the olfactomedin-related protein family and found to be selectively expressed in inflammed colonic epithelium. It has one signal peptide, six N-linked glycosylation motif and forms disulfide-bonded multimers. OLFM4 a transcription factor may have a matrix-related function in differentiation. Constitutively expressed OLFM4 in cancer cells binds to the potent apoptosis inducer GRIM-19 and has a novel antiapoptotic action and hence might serve as a diagnostic marker for human cancers. Reports suggest that OLFM4 promotes proliferation of PANC-1 cells by favoring transition from the S to G2/M phase. Potential interaction of OLFM4 with endogenous cell surface lectins and cadherins may mediate cell adhesion.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OLFM4
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene OLFM4
Gene Accession No. Q6UX06
Gene Alias Antiapoptotic protein GW112; bA209J19.1; GC1; G-CSF-stimulated clone 1 protein; Gm296; Gm913; GW112; hGC-1; hOLfD; olfactomedin 4; olfactomedin-4; OlfD; OLFM4; OLM4; pPD4; PU.1 difference product 4; UNQ362; UNQ362/PRO698
Gene Symbols OLFM4
Host Species Rabbit
Immunogen Synthetic 16 amino acid peptide from internal region of human OLFM4.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10562
Target Species Human, Non-human Primate
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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