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Invitrogen™ OLIG2 Monoclonal Antibody (1G11)
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Catalog No. PIMA515810
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100 μL
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PIMA515810 100 μL
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Catalog No. PIMA515810 Supplier Invitrogen™ Supplier No. MA515810
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Description

Mouse Monoclonal Antibody

MA5-15810 targets OLIG2 in indirect ELISA, IF, IHC, and WB applications and shows reactivity with Human samples. The MA5-15810 immunogen is purified recombinant fragment of human OLIG2 expressed in E. Coli. MA5-15810 detects OLIG2 which has a predicted molecular weight of approximately 32kDa.

This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Tissue specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OLIG2
Applications ELISA, Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Monoclonal
Clone 1G11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene OLIG2
Gene Accession No. Q13516
Gene Alias AI604895; basic domain, helix-loop-helix protein, class B, 1; Basic helix loop helix protein class B1 (bHLHB1); basic helix-loop-helix protein 19 (bHLHe19); bHLH transcription factor; BHLHB1; bHLHe19; Class B basic helix-loop-helix protein 1; class E basic helix-loop-helix protein 19; human protein kinase C-binding protein RACK17; Olg-2; OLIG2; olig-2; Oligo2; Oligo2 antibody; oligodendrocyte lineage transcription factor 2; Oligodendrocyte specific bHLH transcription factor 2; oligodendrocyte transcription factor 2; oligodendrocyte-specific bHLH transcription factor 2; PRKCBP2; Protein kinase C-binding protein 2; Protein kinase C-binding protein 2 (PRKCBP2); Protein kinase C-binding protein RACK17; RACK17; RK17; wu:fc64g09
Gene Symbols OLIG2
Host Species Mouse
Immunogen Purified recombinant fragment of human OLIG2 expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10215
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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