OLIG2 Mouse anti-Human, Mouse, Rat, Clone: 1E8C5, Proteintech

Mouse Monoclonal Antibody

Supplier:  Proteintech Group Inc 665131IG150UL

Catalog No. 50-173-6935

Description

This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Tissue specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.

Specifications

• Antigen: OLIG2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q13516, Q9EQW6
• Gene Symbols: Olig2
• Immunogen: OLIG2 Fusion Protein Ag18838
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 1E8C5
• Conjugate: Unconjugated
• Gene: OLIG2
• Gene Alias: BHLHB1, bHLHe19, OLIG2, OLIGO2, PRKCBP2, RACK17
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 10215, 304103, 50913
• Content And Storage: -20°C
• Form: Liquid