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OLIG2 Mouse anti-Human, Mouse, Rat, Clone: 1E8C5, Proteintech
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Catalog No. 501736935 Shop All Proteintech Group Inc Products
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50-173-6935 150 μL
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Catalog No. 50-173-6935 Supplier Proteintech Group Inc Supplier No. 665131IG150UL
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Mouse Monoclonal Antibody

This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Tissue specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.

Specifications

Antigen OLIG2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1E8C5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene OLIG2
Gene Accession No. Q13516, Q9EQW6
Gene Alias BHLHB1, bHLHe19, OLIG2, OLIGO2, PRKCBP2, RACK17
Gene Symbols Olig2
Host Species Mouse
Immunogen OLIG2 Fusion Protein Ag18838
Purification Method Protein A
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10215, 304103, 50913
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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