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Invitrogen™ OLIG3 Polyclonal Antibody
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Catalog No. PIPA568726
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PIPA568726 100 μL
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Catalog No. PIPA568726 Supplier Invitrogen™ Supplier No. PA568726
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Rabbit Polyclonal Antibody

This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%.

Oligodendrocyte transcription factor 3 (OLIG3) is a gene located on chromosome 6q23.2, encoding a basic helix-loop-helix (bHLH) transcription factor that is involved in the regulation of neural development. OLIG3 is a member of the OLIG family, which plays a significant role in the differentiation and maturation of oligodendrocytes, the myelinating cells of the central nervous system. This transcription factor is crucial for the specification and development of certain neuronal subtypes, contributing to the formation and maintenance of the central nervous system's architecture. OLIG3's activity influences gene expression related to neural proliferation, survival, and differentiation. Although less studied than OLIG1 and OLIG2, OLIG3's expression patterns suggest its involvement in neural patterning and potential roles in neuronal disorders. Research continues to explore the mechanisms through which OLIG3 affects neural development and its implications in neuropathologies and regenerative medicine.
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Specifications

Antigen OLIG3
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene OLIG3
Gene Accession No. 0
Gene Alias basic helix-loop-helix domain-containing class B protein 7; Bhlhb7; bHLHe20; bHLHe20oligo3; Class B basic helix-loop-helix protein 7; class E basic helix-loop-helix protein 20; OLIG3; Oligo3; oligodendrocyte transcription factor 2; oligodendrocyte transcription factor 2; oligodendrocyte transcription factor 3; oligodendrocyte transcription factor 3; Oligodendrocyte-specific bHLH transcription factor 3
Gene Symbols OLIG3
Host Species Rabbit
Immunogen synthetic peptide directed towards the middle region of human OLIG3.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 293012
Target Species Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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