Invitrogen™ OLIG3 Recombinant Rabbit Monoclonal Antibody (9C1N3)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA542609

Catalog No. PIMA542609

Description

Positive test controls include: U-251MG. The target is usually found in the following locations: Nucleus. Immunogen sequence: HAANSVHPVH PILGGALSSG NASSPLSAAS LPAIGTIRPP HSLLKAPSTP PALQLGSGFQ HWAGLPCPCT ICQMPPPPHL SALSTANMAR LSAESKDLLK.

Oligodendrocyte transcription factor 3 (OLIG3) is a gene located on chromosome 6q23.2, encoding a basic helix-loop-helix (bHLH) transcription factor that is involved in the regulation of neural development. OLIG3 is a member of the OLIG family, which plays a significant role in the differentiation and maturation of oligodendrocytes, the myelinating cells of the central nervous system. This transcription factor is crucial for the specification and development of certain neuronal subtypes, contributing to the formation and maintenance of the central nervous system's architecture. OLIG3's activity influences gene expression related to neural proliferation, survival, and differentiation. Although less studied than OLIG1 and OLIG2, OLIG3's expression patterns suggest its involvement in neural patterning and potential roles in neuronal disorders. Research continues to explore the mechanisms through which OLIG3 affects neural development and its implications in neuropathologies and regenerative medicine.

Specifications

• Antigen: OLIG3
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q7RTU3
• Gene Symbols: OLIG3
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 173-272 of human Olig3 (Q7RTU3).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 9C1N3
• Conjugate: Unconjugated
• Gene: OLIG3
• Gene Alias: basic helix-loop-helix domain-containing class B protein 7; Bhlhb7; bHLHe20; bHLHe20oligo3; Class B basic helix-loop-helix protein 7; class E basic helix-loop-helix protein 20; OLIG3; Oligo3; oligodendrocyte transcription factor 2; oligodendrocyte transcription factor 2; oligodendrocyte transcription factor 3; oligodendrocyte transcription factor 3; Oligodendrocyte-specific bHLH transcription factor 3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 167826
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid