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Invitrogen™ Oligodendrocyte Marker O1 Monoclonal Antibody (O1), eBioscience™

Catalog No. 14650637
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2 mg
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14-650-637 2 mg
50-134-86 100 μg
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Catalog No. 14-650-637 Supplier Invitrogen™ Supplier No. 14650637
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Mouse Monoclonal Antibody

Description: This O1 monoclonal antibody reacts with galactocerebroside and other lipids found on late oligodendrocyte precursors. O1 has been reported to react to all species tested (rat, mouse, human, chicken). Oligodendrocytes function as myelin-producing cells within the central nervous system ensheathing the axons of neurons with myelin in order to facilitate rapid axonal conduction. O1 and O4 monoclonal antibodies serve as stage-specific markers of oligodendrocyte development with O4 marking early oligodendrocyte progenitors and O1-labeling late oligodendrocyte progenitors. O4-positive cells differentiate to become O1-positive, which can in turn become mature oligodendrocytes. Applications Reported: This O1 antibody has been reported for use in flow cytometric analysis, immunohistochemical staining of frozen tissue sections, ELISA, and immunocytochemistry. Applications Tested: This O1 antibody has been tested by immunocytochemistry on formaldehyde-fixed, differentiated OLN93 cells and can be used at less than or equal to 10 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered.

Oligodendrocytes function as myelin-producing cells within the central nervous system ensheathing the axons of neurons with myelin in order to facilitate rapid axonal conduction. O1 and O4 monoclonal antibodies serve as stage-specific markers of oligodendrocyte development with O4 marking early oligodendrocyte progenitors and O1-labeling late oligodendrocyte progenitors. O4-positive cells differentiate to become O1-positive, which can in turn become mature oligodendrocytes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Oligodendrocyte Marker O1
Applications ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunocytochemistry
Classification Monoclonal
Clone O1
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene Alias O1 Marker
Host Species Mouse
Purification Method Affinity Chromatography
Quantity 2 mg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human, Mouse, Rat, Chicken
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgM
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