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Oligomycin, MP Biomedicals™

Catalog Number mp215178625
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Quantity:
25 mg
1404-19-9
C45H74O11
791.08
MFCD00065705,MFCD01779388
MNULEGDCPYONBU-ZUSSGZTJNA-N
Olivomycin, Aburamycin
78358496
(4E,18E,20Z)-22-ethyl-7,11,14,15-tetrahydroxy-6'-(2-hydroxypropyl)-5',6,8,10,12,14,16,28,29-nonamethyl-2,26-dioxaspiro[bicyclo[23.3.1]nonacosane-27,2'-oxane]-4,18,20-triene-3,9,13-trione
CCC1CCC2OC3(CCC(C)C(CC(C)O)O3)C(C)C(OC(=O)\C=C\C(C)C(O)C(C)C(=O)C(C)C(O)C(C)C(=O)C(C)(O)C(O)C(C)C\C=C\C=C/1)C2C
1404-19-9
C45H74O11
791.08
MFCD00065705,MFCD01779388
MNULEGDCPYONBU-ZUSSGZTJNA-N
Olivomycin, Aburamycin
78358496
(4E,18E,20Z)-22-ethyl-7,11,14,15-tetrahydroxy-6'-(2-hydroxypropyl)-5',6,8,10,12,14,16,28,29-nonamethyl-2,26-dioxaspiro[bicyclo[23.3.1]nonacosane-27,2'-oxane]-4,18,20-triene-3,9,13-trione
CCC1CCC2OC3(CCC(C)C(CC(C)O)O3)C(C)C(OC(=O)\C=C\C(C)C(O)C(C)C(=O)C(C)C(O)C(C)C(=O)C(C)(O)C(O)C(C)C\C=C\C=C/1)C2C

Description

Inhibits mitochondrial ATPase and phosphoryl group transfer. Oligomycin, MP Biomedicals is a natural antibiotic isolated from Streptomyces diastatochromogenes. It is a mixture of oligomycins A, B, and C.

Oligomycin is used as antibiotic which inhibits respiration in mitochondria. It inhibits ATP synthase by blocking its proton channel (F0 subunit), which is necessary for oxidative phosphorylation of ADP to ATP (energy production).

Physical Form Powder
Melting Point 150°C (literature)
Source Streptomyces diastatochromogenes
Solubility Information Soluble in ether, benzene, absolute ethanol, glacial acetic acid and acetone.
Formula Weight ∼789.3
Quantity 25 mg

Safety and Handling

Recommended Storage Store at 4°C.
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