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Olmesartan, Tocris Bioscience™

Catalog No. 461650
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Quantity:
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent AT1 antagonist; metabolite of Olmesartan medoxomil (Cat. No. 4620)

Potent angiotensin II type I (AT1) receptor antagonist (IC50 = 6.7 nM at hAT1 receptors). Improves cognitive function in a mouse model of hypertension- and hyperlipidemia-associated cognitive decline; ameliorates arterial stiffness in a rat model of chronic renal failure.

Chemical Identifiers

CAS 144689-24-7
Molecular Formula C24H26N6O3
Molecular Weight (g/mol) 446.51
MDL Number MFCD00914967
InChI Key VTRAEEWXHOVJFV-UHFFFAOYSA-N
Synonym olmesartan, olmesartan acid, votum, olme sartan, unii-8w1iqp3u10, chembl1516, 4-2-hydroxypropan-2-yl-2-propyl-1-4-2-1h-1,2,3,4-tetrazol-5-yl phenyl phenyl methyl-1h-imidazole-5-carboxylic acid, 1-2'-1h-tetrazol-5-yl-1,1'-biphenyl-4-yl methyl-4-2-hydroxypropan-2-yl-2-propyl-1h-imidazole-5-carboxylic acid, 1h-imidazole-5-carboxylic acid, 4-1-hydroxy-1-methylethyl-2-propyl-1-2'-1h-tetrazol-5-yl 1,1'-biphenyl-4-yl methyl, 4-1-hydroxy-1-methylethyl-2-propyl-1-2'-2h-tetrazol-5-yl 1,1'-biphenyl-4-yl methyl-1h-imidazole-5-carboxylic acid
PubChem CID 158781
ChEBI CHEBI:48416
IUPAC Name 4-(2-hydroxypropan-2-yl)-2-propyl-1-{[2'-(2H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1H-imidazole-5-carboxylic acid
SMILES CCCC1=NC(=C(N1CC1=CC=C(C=C1)C1=CC=CC=C1C1=NNN=N1)C(O)=O)C(C)(C)O

Specifications

Quantity 50 mg
Formula Weight 446.5
Percent Purity >99%
Chemical Name or Material Olmesartan

Safety and Handling

Recommended Storage Store at +4°C
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