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Invitrogen™ Oncostatin M Monoclonal Antibody (17001)
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Catalog No. PIMA523810
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100 μg
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Catalog No. Quantity
PIMA523810 100 μg
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Catalog No. PIMA523810 Supplier Invitrogen™ Supplier No. MA523810
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Description

Mouse Monoclonal Antibody

In ELISAs, this antibody does not cross-react with recombinant human (rh) IL-6, rhIL-11, rhCNTF, or rhLIF. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptors in hepatoma cells. OSM shares several structural and functional characteristics with LIF, IL-6, and CNTF.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Oncostatin M
Applications ELISA, Neutralization, Western Blot
Classification Monoclonal
Clone 17001
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene OSM
Gene Accession No. P13725
Gene Alias MGC20461; OncoM; oncostatin M; oncostatin-M; OSM
Gene Symbols OSM
Host Species Mouse
Immunogen E. coli-derived recombinant human Oncostatin M/OSM Ala26-Arg234.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5008
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2a
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