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Invitrogen™ Oncostatin M Monoclonal Antibody (17001)
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Catalog No. PIMA124832
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100 μg
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Catalog No. Quantity
PIMA124832 100 μg
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Catalog No. PIMA124832 Supplier Invitrogen™ Supplier No. MA124832
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Description

Mouse Monoclonal Antibody

MA1-24832 will not react with mouse. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptors in hepatoma cells. OSM shares several structural and functional characteristics with LIF, IL-6, and CNTF.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Oncostatin M
Applications ELISA, Neutralization, Western Blot
Classification Monoclonal
Clone 17001
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and no preservative
Gene OSM
Gene Accession No. P13725
Gene Alias MGC20461; OncoM; oncostatin M; oncostatin-M; OSM
Gene Symbols OSM
Host Species Mouse
Immunogen Recombinant human OSM expressed in Escherichia coli.
Purification Method Purified
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5008
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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