Invitrogen™ Oncostatin M Polyclonal Antibody

Catalog No.	Quantity
PIPA5120974	100 μL

Catalog No. PIPA5120974 Supplier Invitrogen™ Supplier No. PA5120974

Description

Rabbit Polyclonal Antibody

Positive test controls include: HepG2, NIH/3T3, Mouse uterus, Mouse heart. The target is usually found in the following locations: Secreted.

Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptors in hepatoma cells. OSM shares several structural and functional characteristics with LIF, IL-6, and CNTF.

Specifications

• Antigen: Oncostatin M
• Applications: ELISA, Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.19 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: OSM
• Gene Accession No.: P13725, P53347, Q65Z15
• Gene Alias: MGC20461; OncoM; oncostatin M; oncostatin-M; OSM
• Gene Symbols: OSM
• Host Species: Rabbit
• Immunogen: Recombinant protein (or fragment).
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 18413, 289747, 5008
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG