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Invitrogen™ Oncostatin M Polyclonal Antibody
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Catalog No. PIPA579773
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100 μg
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PIPA579773 100 μg
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Catalog No. PIPA579773 Supplier Invitrogen™ Supplier No. PA579773
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: A549 whole cell, A549 whole cell, HELA whole cell. IHC: Human Intestinal Cancer Tissue.

Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptors in hepatoma cells. OSM shares several structural and functional characteristics with LIF, IL-6, and CNTF.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Oncostatin M
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
Gene OSM
Gene Accession No. P13725
Gene Alias MGC20461; OncoM; oncostatin M; oncostatin-M; OSM
Gene Symbols OSM
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence in the middle region of human Oncostatin M (181-198aa ASDAFQRKLEGCRFLHGY).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5008
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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