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Oncostatin M Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

$250.00 - $2175.00

Specifications

Antigen Oncostatin M
Concentration 0.1-1.0 mg/mL
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Biotin
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
500P30BT25
Encompass_Preferred
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Invitrogen™
500P30BT25UG
25 μg
Each for $250.00
Only null left
Add to Cart
 
50-271-8523
Encompass_Preferred
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Invitrogen™
500P30BT500UG
500 μg
Each for $2,175.00
Only null left
Add to Cart
 
Description

Description

AA Sequence of recombinant protein: AAIGSCSKEY RVLLGQLQKQ TDLMQDTSRL LDPYIRIQGL DVPKLREHCR ERPGAFPSEE TLRGLGRRGF LQTLNATLGC VLHRLADLEQ RLPKAQDLER SGLNIEDLEK LQMARPNILG LRNNIYCMAQ LLDNSDTAEP TKAGRGASQP PTPTPASDAF QRKLEGCRFL HGYHRFMHSV GRVFSKWGES PNRSRRHSPH QALRKGVRRT RPSRKGKRLM TRGQLPR. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human Oncostatin M. Anti-Human Oncostatin M-specific antibody was purified by affinity chromatography and then biotinylated. Sandwich ELISA: To detect hOncostatin M by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human Oncostatin M (500-P30) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant hOncostatin M. Western Blot: To detect hOncostatin M by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant hOncostatin M is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. 500-P30BT-1MG will be provided as 2 x 500 μg

Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptors in hepatoma cells. OSM shares several structural and functional characteristics with LIF, IL-6, and CNTF.
Specifications

Specifications

Oncostatin M
ELISA, Western Blot
Biotin
Rabbit
Human
P13725
5008
E.coli-derived, 25.7 kDa Recombinant Human Oncostatin M.
Antigen affinity chromatography
OSM
0.1-1.0 mg/mL
Polyclonal
Lyophilized
RUO
PBS with no preservative
MGC20461; OncoM; oncostatin M; oncostatin-M; OSM
OSM
Primary
-20°C
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SDS
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