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  5. Tocris Bioscience™ Ondansetron hydrochloride

Tocris Bioscience™ Ondansetron hydrochloride
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Catalog No. 289150
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Selective 5-HT3 antagonist

Ondansetron hydrochloride is a selective 5-HT3 receptor antagonist (Ki = 6.16 nM). Also an inhibitor of human multidrug and toxin extrusion (MATE) transporter 1 (IC50 = <10-160 nM). Ondansetron blocks 5-HT-evoked transient inward currents (IC50 = 0.1 nM) in human recombinant h5-HT3A receptors. In an animal model of Parkinson's disease, Ondansetron reduces both the severity of dyskinesia and psychosis-like behaviors. Antiemetic; prevents emesis induced by cytotoxic drugs and radiation.

Chemical Identifiers

CAS 99614-01-4
Molecular Formula C18H20ClN3O

Specifications

Quantity 50 mg
Formula Weight 329.83
Purity >99%
Molecular Weight (g/mol) 329.83
Chemical Name or Material Ondansetron hydrochloride

Safety and Handling

Recommended Storage Store at Room Temperature
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