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Invitrogen™ OPHN1 Polyclonal Antibody
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Catalog No. PIPA5100164
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100 μL
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PIPA5100164 100 μL
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Catalog No. PIPA5100164 Supplier Invitrogen™ Supplier No. PA5100164
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Oligophrenin 1.

Stimulates GTP hydrolysis of members of the Rho family. Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function. Critical for the stabilization of AMPA receptors at postsynaptic sites. Critical for the regulation of synaptic vesicle endocytosis at presynaptic terminals. Required for the localization of NR1D1 to dendrites, can suppress its repressor activity and protect it from proteasomal degradation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OPHN1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene OPHN1
Gene Accession No. O60890, P0CAX5, Q99J31
Gene Alias ARHGAP41; C130037N19Rik; mental retardation, X-linked 60; MRX60; oligophrenin 1; oligophrenin-1; oligophrenin-1, Rho-GTPase activating protein; Ophn1; Opn1
Gene Symbols OPHN1
Host Species Rabbit
Immunogen A synthesized peptide derived from human OPHN1(Accession O60890), corresponding to amino acid residues L222-L272.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 312108, 4983, 94190
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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