Invitrogen™ OPRD1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA14558

Catalog No. PA14558

Description

PA1-4558 detects delta Opioid Receptor from human, mouse, and rat samples. PA1-4558 has been successfully used in Western blotting applications. This antibody will detect a dominant band of ~48 kDa representing the monomer form of DOR-1, and may also detect dimmers or trimers as heterodimerization and homodimerization is common The PA1-4558 immunogen is a synthetic peptide corresponding to residues 3-17 L(3) V P S A R A E L Q S S P L V(17) of mouse and rat DOR-1.

OPRD1 is an Opioid Receptor that is involved in the control of anxiety, depression, and pain. It is a promising target in the therapy of mood-altering disorders and drug addiction. Delta and kappa opioid receptors function synergistically by forming heterodimers. OPRD1 expression has been reported primarily in the brain. High OPRD1 expression has been documented in the cortex, caudate, hippocampus, nucleus accumbens, and putamen; low OPRD1 expression has been identified in the cerebellum, hypothalamus, substantia nigra, and thalamus. OPRD1 expression is reduced in the putamen and amygdala of Alzheimer's patients and in the putamen in Parkinson's disease.

Specifications

• Antigen: OPRD1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: OPRD1
• Gene Alias: delta 1 opioid receptor; delta opioid receptor 1; delta-type opioid receptor; DOR; D-OR-1; DOR-1; K56; mDOR; MSL-2; Nbor; Opioid receptor; opioid receptor A; opioid receptor delta 1; opioid receptor, delta 1; OPRD; Oprd1; Ror-a
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18386, 24613, 4985
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: P32300, P33533, P41143
• Gene Symbols: OPRD1
• Immunogen: Synthetic peptide corresponding to residues L(3) V P S A R A E L Q S S P L V(17) of mouse and rat DOR-1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG