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Invitrogen™ OPRD1 Polyclonal Antibody
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Catalog No. PA14558
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100 μg
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PA14558 100 μg
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Catalog No. PA14558 Supplier Invitrogen™ Supplier No. PA14558
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Description

Rabbit Polyclonal Antibody

PA1-4558 detects delta Opioid Receptor from human, mouse, and rat samples. PA1-4558 has been successfully used in Western blotting applications. This antibody will detect a dominant band of ~48 kDa representing the monomer form of DOR-1, and may also detect dimmers or trimers as heterodimerization and homodimerization is common The PA1-4558 immunogen is a synthetic peptide corresponding to residues 3-17 L(3) V P S A R A E L Q S S P L V(17) of mouse and rat DOR-1.

OPRD1 is an Opioid Receptor that is involved in the control of anxiety, depression, and pain. It is a promising target in the therapy of mood-altering disorders and drug addiction. Delta and kappa opioid receptors function synergistically by forming heterodimers. OPRD1 expression has been reported primarily in the brain. High OPRD1 expression has been documented in the cortex, caudate, hippocampus, nucleus accumbens, and putamen; low OPRD1 expression has been identified in the cerebellum, hypothalamus, substantia nigra, and thalamus. OPRD1 expression is reduced in the putamen and amygdala of Alzheimer's patients and in the putamen in Parkinson's disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OPRD1
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene OPRD1
Gene Accession No. P32300, P33533, P41143
Gene Alias delta 1 opioid receptor; delta opioid receptor 1; delta-type opioid receptor; DOR; D-OR-1; DOR-1; K56; mDOR; MSL-2; Nbor; Opioid receptor; opioid receptor A; opioid receptor delta 1; opioid receptor, delta 1; OPRD; Oprd1; Ror-a
Gene Symbols OPRD1
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues L(3) V P S A R A E L Q S S P L V(17) of mouse and rat DOR-1.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18386, 24613, 4985
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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