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Invitrogen™ OPRK1 Polyclonal Antibody
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Catalog No. PIPA533860
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50 μg
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PIPA533860 50 μg
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Catalog No. PIPA533860 Supplier Invitrogen™ Supplier No. PA533860
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Dog, Horse, Rabbit (100%); Gorilla, Mouse, Rat, Elephant, Guinea pig (95%); Bat, Bovine, Panda (89%); Opossum (84%). Please note that this antibody produces faint nuclear background staining in some tissues.

This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OPRK1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene OPRK1
Gene Accession No. P34975, P41145
Gene Alias kappa opioid receptor; kappa-type opioid receptor; KOPR1; KOR; K-OR-1; KOR-1; MSL-1; Opiate receptor, kappa-1; opioid receptor kappa 1; opioid receptor, kappa 1; opioid receptor, kappa 2; OPRK; OPRK1; Oprk2; Ork1; R21; Ror-d
Gene Symbols OPRK1
Host Species Rabbit
Immunogen Synthetic 19 amino acid peptide from 2nd extracellular domain of human Kappa Opioid Receptor.
Purification Method Antigen Affinity Chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100054492, 100354170, 29335, 486951, 4986
Target Species Human, Rat, Canine, Rabbit, Monkey, Horse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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