Invitrogen™ Opsin 3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA532956

Catalog No. PIPA532956

Description

Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Rat (100%); Mouse, Dog, Panda, Rabbit (94%); Horse, Opossum (88%); Turkey (81%). For IHC(P), use proteinase K antigen retrieval. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in extraocular tissues. This gene, opsin 3, is strongly expressed in brain and testis and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. The gene may also be expressed in the retina. The protein has the canonical features of a photoreceptive opsin protein. May play a role in encephalic photoreception. Strongly expressed in brain. Highly expressed in the preoptic area and paraventricular nucleus of the hypothalamus. Shows highly patterned expression in other regions of the brain, being enriched in selected regions of the cerebral cortex, cerebellar Purkinje cells, a subset of striatal neurons, selected thalamic nuclei, and a subset of interneurons in the ventral horn of the spinal cord.

Specifications

• Antigen: Opsin 3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Opn3
• Gene Alias: ECPN; Encephalopsin; ERO; NMO-1; Opn3; opsin (encephalopsin); opsin 3; opsin 3 (encephalopsin, panopsin); opsin-3; Panopsin; PPP1R116; protein phosphatase 1, regulatory subunit 116
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23596, 498289
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q9H1Y3
• Gene Symbols: Opn3
• Immunogen: Synthetic 16 amino acid peptide from internal region of human OPN3 / Encephalopsin.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat, Monkey
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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