Invitrogen™ Opticin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA537262

Catalog No. PIPA537262

Description

This antibody detects endogenous protein at a molecular weight of 40 kDa. Purity is >95% by SDS-PAGE.

Opticin, also known as OPTC or OPT, is a 332 amino acid protein that is secreted into the extracellular matrix and contains seven LRR repeats. Expressed in skin and fetal liver and also present in ocular tissues, such as the retina, cornea and iris, opticin functions to bind collagen fibrils and, via this interaction, is thought to regulate fibril spacing, morphology and organization. Opticin is subject to post-translational O-glycosylation and may be associated with the pathogenesis of primary open angle glaucoma.

Specifications

• Antigen: Opticin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: OPTC
• Gene Alias: dermatan sulfate proteoglycan 3; dspg3; Oculoglycan; OPT; Optc; optcl; opticin; SLRP; SLRP protein; small leucine-rich repeat protein; small leucine-rich repeat protein (SLRP); wu:fb81a05; zgc:101047
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26254, 269120, 304802
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q920A0, Q9UBM4
• Gene Symbols: OPTC
• Immunogen: A synthetic peptide corresponding to residues in human Opticin.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG