Invitrogen™ Opticin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA544262

Catalog No. PIPA544262

Description

Peptide sequence: LSDNLLDSIP GPLPLSLRSV HLQNNLIETM QRDVFCDPEE HKHTRRQLED Sequence homology: Cow: 77%; Dog: 100%; Guinea Pig: 85%; Horse: 92%; Human: 100%; Mouse: 85%; Pig: 100%; Rabbit: 92%; Rat: 100%; Zebrafish: 83%.

Opticin, also known as OPTC or OPT, is a 332 amino acid protein that is secreted into the extracellular matrix and contains seven LRR repeats. Expressed in skin and fetal liver and also present in ocular tissues, such as the retina, cornea and iris, opticin functions to bind collagen fibrils and, via this interaction, is thought to regulate fibril spacing, morphology and organization. Opticin is subject to post-translational O-glycosylation and may be associated with the pathogenesis of primary open angle glaucoma.

Specifications

• Antigen: Opticin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: OPTC
• Gene Alias: dermatan sulfate proteoglycan 3; dspg3; Oculoglycan; OPT; Optc; optcl; opticin; SLRP; SLRP protein; small leucine-rich repeat protein; small leucine-rich repeat protein (SLRP); wu:fb81a05; zgc:101047
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26254
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9UBM4
• Gene Symbols: OPTC
• Immunogen: Synthetic peptide directed towards the C-terminal of human OPTC (aa 254-303).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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