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Invitrogen™ Opticin Polyclonal Antibody
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Catalog No. PIPA544262
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100 μL
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PIPA544262 100 μL
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Catalog No. PIPA544262 Supplier Invitrogen™ Supplier No. PA544262
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Rabbit Polyclonal Antibody

Peptide sequence: LSDNLLDSIP GPLPLSLRSV HLQNNLIETM QRDVFCDPEE HKHTRRQLED Sequence homology: Cow: 77%; Dog: 100%; Guinea Pig: 85%; Horse: 92%; Human: 100%; Mouse: 85%; Pig: 100%; Rabbit: 92%; Rat: 100%; Zebrafish: 83%.

Opticin, also known as OPTC or OPT, is a 332 amino acid protein that is secreted into the extracellular matrix and contains seven LRR repeats. Expressed in skin and fetal liver and also present in ocular tissues, such as the retina, cornea and iris, opticin functions to bind collagen fibrils and, via this interaction, is thought to regulate fibril spacing, morphology and organization. Opticin is subject to post-translational O-glycosylation and may be associated with the pathogenesis of primary open angle glaucoma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Opticin
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene OPTC
Gene Accession No. Q9UBM4
Gene Alias dermatan sulfate proteoglycan 3; dspg3; Oculoglycan; OPT; Optc; optcl; opticin; SLRP; SLRP protein; small leucine-rich repeat protein; small leucine-rich repeat protein (SLRP); wu:fb81a05; zgc:101047
Gene Symbols OPTC
Host Species Rabbit
Immunogen Synthetic peptide directed towards the C-terminal of human OPTC (aa 254-303).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26254
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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