Invitrogen™ Opticin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA557091

Catalog No. PIPA557091

Description

Immunogen sequence: RIDLSNNLIS SIDNDAFRLL HALQDLILPE NQLEALPVLP SGIEFLDVRL NRLQSSGIQP AAFRAMEKLQ FLYLSDNLLD SIP Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 86%.

Opticin, also known as OPTC or OPT, is a 332 amino acid protein that is secreted into the extracellular matrix and contains seven LRR repeats. Expressed in skin and fetal liver and also present in ocular tissues, such as the retina, cornea and iris, opticin functions to bind collagen fibrils and, via this interaction, is thought to regulate fibril spacing, morphology and organization. Opticin is subject to post-translational O-glycosylation and may be associated with the pathogenesis of primary open angle glaucoma.

Specifications

• Antigen: Opticin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: OPTC
• Gene Alias: dermatan sulfate proteoglycan 3; dspg3; Oculoglycan; OPT; Optc; optcl; opticin; SLRP; SLRP protein; small leucine-rich repeat protein; small leucine-rich repeat protein (SLRP); wu:fb81a05; zgc:101047
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26254
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UBM4
• Gene Symbols: OPTC
• Immunogen: Recombinant protein corresponding to Human Opticin. Recombinant protein control fragment (Product #RP-94534).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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