Invitrogen™ Opticin Polyclonal Antibody

Catalog No.	Quantity
PIPA5110061	100 μL

Catalog No. PIPA5110061 Supplier Invitrogen™ Supplier No. PA5110061

Description

Rabbit Polyclonal Antibody

Immunogen sequence: ASLPRKERKR REEQMPREGD SFEVLPLRND VLNPDNYGEV IDLSNYEELT DYGDQLPEVK VTSLAPATSI SPAKSTTAPG TPSSNPTMTR PTTAGL.

Opticin, also known as OPTC or OPT, is a 332 amino acid protein that is secreted into the extracellular matrix and contains seven LRR repeats. Expressed in skin and fetal liver and also present in ocular tissues, such as the retina, cornea and iris, opticin functions to bind collagen fibrils and, via this interaction, is thought to regulate fibril spacing, morphology and organization. Opticin is subject to post-translational O-glycosylation and may be associated with the pathogenesis of primary open angle glaucoma.

Specifications

• Antigen: Opticin
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 1.9 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene: OPTC
• Gene Accession No.: Q920A0
• Gene Alias: dermatan sulfate proteoglycan 3; dspg3; Oculoglycan; OPT; Optc; optcl; opticin; SLRP; SLRP protein; small leucine-rich repeat protein; small leucine-rich repeat protein (SLRP); wu:fb81a05; zgc:101047
• Gene Symbols: OPTC
• Host Species: Rabbit
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-115 of human OPTC (NP_055174.1).
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 269120, 304802
• Target Species: Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG