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OPTN Mouse anti-Human, Biotin, Clone: 6C1H4, Proteintech
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Catalog No. 501737227 Shop All Proteintech Group Inc Products
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50-173-7227 100 μL
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Catalog No. 50-173-7227 Supplier Proteintech Group Inc Supplier No. BIOTIN60293100UL
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Description

Mouse Monoclonal Antibody

This antibody is conjugated with Biotin.

This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.

Specifications

Antigen OPTN
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 6C1H4
Concentration 0.73 mg/mL
Conjugate Biotin
Formulation PBS with 50% glycerol and no preservative; pH 7.3
Gene OPTN
Gene Accession No. Q96CV9
Gene Alias FIP 2, optineurin, OPTN
Gene Symbols OPTN
Host Species Mouse
Immunogen OPTN Fusion Protein Ag1272
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10133
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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