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OPTN Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 50559136 Shop All Proteintech Group Inc Products
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50-559-136 150 μL
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Catalog No. 50-559-136 Supplier Proteintech Group Inc Supplier No. 108371AP150UL
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Description

Rabbit Polyclonal Antibody

10837-1-AP recognizes 66 and 70-74 kDa band. The additional 70-74 kDa band is due to phosphorylation.

This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14. 7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.

Specifications

Antigen OPTN
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Classification Polyclonal
Concentration 0.35 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene OPTN
Gene Accession No. Q8K3K8, Q8R5M4, Q96CV9
Gene Alias E3 14.7K interacting protein, FIP 2, FIP2, GLC1E, HIP 7, HIP7, Huntingtin yeast partner L, HYPL, NEMO related protein, NRP, optineurin, OPTN, TFIIIA INTP
Gene Symbols Optn
Host Species Rabbit
Immunogen OPTN Fusion Protein Ag1272
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10133, 246294, 71648
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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