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ORAI2 Monoclonal Antibody (OTI8D11), TrueMAB™, OriGene
SDP

Catalog No. 501681581
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100 μL
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50-168-1581 100 μL
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Catalog No. 50-168-1581 Supplier OriGene Supplier No. TA807500
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Mouse Monoclonal Antibody

Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1.

Specifications

Antigen ORAI2
Applications Western Blot
Classification Monoclonal
Clone OTI8D11
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene ORAI2
Gene Accession No. Q96SN7
Gene Alias C7orf19, CBCIP2, MEM142B, TMEM142B
Gene Symbols ORAI2
Host Species Mouse
Immunogen Full length human recombit protein of human ORAI2 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80228
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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