ORAI2 Mouse anti-Human, Clone: OTI8D11, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF807500

Catalog No. 50-166-8303

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1.

Specifications

• Antigen: ORAI2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: ORAI2
• Gene Alias: C7orf19, CBCIP2, MEM142B, TMEM142B
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 80228
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI8D11
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q96SN7
• Gene Symbols: ORAI2
• Immunogen: Full length human recombit protein of human ORAI2 produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b