ORAI2 Mouse anti-Human, Clone: OTI8D11, lyophilized, TrueMAB™

Catalog No.	Quantity
50-166-8303	100 μg

Catalog No. 50-166-8303 Supplier OriGene Supplier No. CF807500

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1.

Specifications

• Antigen: ORAI2
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI8D11
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: ORAI2
• Gene Accession No.: Q96SN7
• Gene Alias: C7orf19, CBCIP2, MEM142B, TMEM142B
• Gene Symbols: ORAI2
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human ORAI2 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 80228
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG2b